ABSTRACT
Uterine leiomyoma is a benign tumor of myometrial tissue which affects women of reproductive age. Its prevalence increases with age and has a peak incidence at the age of forty. The term "metastasizing leiomyoma" refers to a tumor of dense connective tissue and smooth myometrial muscle cells located outside the uterus. This group of tumors can metastasize to different organs, the lung being its main focus. We present the case report of a 33-year-old female gravida 3, para 1, abortus 1, at 11 weeks of pregnancy, with pelvic masses. The diagnosis was metastasizing leiomyoma during pregnancy.
Subject(s)
Humans , Female , Pregnancy , Adult , Leiomyoma/diagnosis , Leiomyosarcoma/diagnosis , Uterine Neoplasms/diagnosis , PregnancyABSTRACT
ABSTRACT BACKGROUND AND OBJECTIVES: The purpose of this study was to evaluate the presence of cognitive deficits in patients with episodic migraine and control group, and to compare with the results previously described in the literature. METHODS: Patients with episodic migraine were included according to the International Headache Society criteria, and a control group was selected, matched by sex, age, and schooling. Patients were asked about the frequency and intensity of headaches, medications used, and comorbidities. Afterwards, a neuropsychological assessment was applied using the Montreal Cognitive Assessment, the clock drawing test, the verbal fluency test, and the Stroop test. The main variables influencing cognitive dysfunctions were analyzed (depressive disorder, anxiety disorder, sleep disorder, use of medication). RESULTS: Thirty patients with episodic migraine and 30 controls were evaluated. Patients with episodic migraine had a performance in the Montreal Cognitive Assessment test (p=0.53), the clock drawing test (p=0.80), the verbal fluency test (p=0.44) and the Stroop test (p=0.97) similar to the control group. Patients with chronic migraine (30 patients and 30 controls) performed a Montreal Cognitive Assessment test (p=0.00), verbal fluency test (p=0.00) and Stroop test (p=0.00) lower than the group control. The main variables influencing cognitive disorders were studied by linear regression, and none of these variables was an influencing factor in the Montreal Cognitive Assessment test. CONCLUSION: Patients with episodic migraine did not present cognitive deficits compared to a control group.
RESUMO JUSTIFICATIVA E OBJETIVOS: A proposta deste estudo foi avaliar a presença de déficits cognitivos em pacientes com migrânea episódica e grupo controle, e comparar com os resultados previamente descritos na literatura. MÉTODOS: Foram incluídos pacientes com migrânea episódica, segundo os critérios da International Headache Society, e selecionado um grupo controle pareado por sexo, idade e escolaridade. Os pacientes foram questionados sobre a frequência e intensidade de crises, fármacos, comorbidades. Posteriormente, foi realizada a avaliação neuropsicológica através do Montreal Cognitive Assessment, do teste do relógio, teste da fluência verbal e Stroop teste. As principais variáveis influenciadoras de distúrbios cognitivos foram analisadas (transtorno depressivo, transtorno de ansiedade, distúrbios do sono, uso de fármacos). RESULTADOS: Foram avaliados 30 pacientes com migrânea episódica e 30 controles. Os pacientes com migrânea episódica apresentaram uma performance no Montreal Cognitive Assessment teste (p=0,53), teste do relógio (p=0,80), teste da fluência verbal (p=0,44) e Stroop teste (p=0,97) semelhante ao grupo controle. Pacientes com enxaqueca crônica (30 pacientes e 30 controles) realizaram um teste de Montreal Cognitive Assessment teste (p=0,00), teste de fluência verbal (p=0,00) e teste de Stroop (p=0,00) menor que o grupo controle. As principais variáveis influenciadoras de distúrbios cognitivos foram estudadas através de regressão linear e nenhuma dessas variáveis apresentou-se como fator de influência no Montreal Cognitive Assessment. CONCLUSÃO: Os pacientes com migrânea episódica não apresentaram déficits cognitivos em comparação com um grupo controle.